Only one other case of desmoplastic ameloblastoma has been reported in the ramus region of mandible of the 90 cases that we have reviewed. Review of. Abstract Desmoplastic Ameloblastoma is a rare histological variant of Ameloblastoma. Approximately cases of desmoplastic Ameloblastoma have been. The desmoplastic ameloblastoma (DA) is characterized by specific clinical, Article· Literature Review (PDF Available) in Oral Oncology.

Author: Kazihn Jubar
Country: Suriname
Language: English (Spanish)
Genre: Personal Growth
Published (Last): 3 November 2014
Pages: 471
PDF File Size: 1.45 Mb
ePub File Size: 7.19 Mb
ISBN: 694-8-62594-159-4
Downloads: 80497
Price: Free* [*Free Regsitration Required]
Uploader: Neran

Clinical features Age and gender distribution Apart from 1 case without mentioned of age, the age and gender distributions of cases DAs were listed in Fig.

Desmoplastic ameloblastoma – A review.

The desmoplastic ameloblastoma DA is characterized revieq specific clinical, imaging, and histological features.

Desmoplastic variant of ameloblastoma in Malaysians. Again, the borders of DA are usually poorly defined.

Histologically, DA is characterized by the presence of extensive stromal collagenization or desmoplasia containing small nests and strands of odontogenic epithelial tissue [ 2 — 6 ].

Radiographic characteristics of cystogenic ameloblastoma. Desmoplastic variant of ameloblastoma: World Health Organization classification of tumors: Yoshimura and Saito Radiologically, there is not any agreement among DA reviews as to whether it deals with a radiolucent or mixed radiolucent— radiopaque lesion.

Hybrid odontogenic tumors might result from the diverse differentiation potentials of odontogenic epithelial cells, whose multipotentiality is demonstrated by the number of different histopathological varieties of odontogenic tumors.


A previous study suggests that desmoplasia within the stromal connective tissue in DA represents a change that occurs during the maturation of conventional ameloblastomas suggesting that the follicular component arises on a desmoplashic background in hybrid ameloblastoma lesions [ 16 ].

Location Anatomical localization was described in cases.

J Desmoplasric Maxillofac Surg There were no post-operative complications. DA exhibiting granular cell transformation in some of the tumor cells has been reported.

This is in contrast to the conventional ameloblastoma which is found predominantly in the posterior region of mandible. A case of desmoplastic variant of a mandibular ameloblastoma.

Nine cases of hybrid ameloblastoma lesions in which areas of conventional ameloblastoma ameloblxstoma with areas of DA were examined with cases of DA. Grade I mobility of 21 and 22 was also noticed. Radiologic features of desmoplastic variant of ameloblastoma. Immunoexpression of transforming growth factor beta in desmoplastic ameloblastoma. The average period until recurrence was The radiological information available for each reviewed case was not uniform. The mean age of DA patients at the initial presentation ranges from 40 to 49, and DA exhibits a similar gender distribution to other ameloblastomas [ 2 — 5 ].

Desmoplastic ameloblastoma with osteoplasia: Review of literature with a case report

However, more systematic studies on DA are needed to verify such suggestions. The age at time of primary presentation ranged from 17 to 83 years with a mean age of Discussion Clinically, DA may develop in all ages, however, people of the 4th and 5th decade are more prone to be affected.


DA may be defined as a benign but locally invasive variant consisting of proliferating, irregular, often bizarrely shaped islands and cords of odontogenic epithelium of varying sizes embedded in a desmoplastic connective tissue stroma. Infrequent clinicopathological findings in ameloblastomas, J Oral Pathol Med, Desmoplastic ameloblastoma in the maxilla: We therefore chose enucleation and curettage and opted for preservation of the inferior alveolar nerve despite understanding the increased risk of tumor recurrence.

It has been reported that DA exhibits more aggressive behavior than other types of ameloblastoma. A case of desmoplastic variant of a mandibular ameloblastoma, J Craniomaxillofac Sorg, However, Escande et al. The lesion histopathologically consisted of areas of desmoplastic ameloblastoma and follicular ameloblastoma and was diagnosed as a hybrid ameloblastoma.

A panoramic radiograph showing a well-defined large radiolucent lesion in the right mandible. On examination, a bony hard swelling was seen in relation to 21, 22 and 23 on the buccal aspect measuring about 2.

Desmoplastic ameloblastoma. A case report and literature review — Johns Hopkins University

A characteristic feature amsloblastoma an almost equal distribution in location between the maxilla and mandible. Unusual ameloblastoma with extensive stromal desmoplasia.

Pathology of the desmoplastic ameloblastoma.

Curran and Byerly 7.